Humeral chondrosarcoma associated with lung metastases in a young dog - case report

ABSTRACT Chondrosarcoma, an unusual malignant neoplasm, develops in cartilaginous tissue and presents low rate of metastasis, mainly affecting the axial skeleton from the adult to senile dogs. In the face of unusual occurrence of chondrosarcoma in the long bones of young dogs, the present report aimed to describe it in the right humerus of a two-and-a-half-year-old Siberian Husky, attended at the Veterinary Hospital of the University of Franca, with limping of the right thoracic limb, for 20 days. The radiographic examination of the humerus showed bone lysis and periosteal proliferation. In the incisional biopsy, proliferation of atypical chondrocytes with diffuse distribution, interspersed with compact bone matrix, was observed. The amputation of the limb was performed, and the fragment histopathological analysis showed grade I chondrosarcoma. Periodic returns were made for neoplastic staging, and at 240 days after surgery lung metastases were detected, however, the tutor did not authorize chemotherapy and radiotherapy for financial reasons and due to the absence of respiratory symptoms so far (410 days after surgery). Although uncommon, chondrosarcoma can affect the long bones of young dogs, with clinical signs similar to other bone neoplasms, and, even with the radical limb amputation, can demonstrate systemic metastasis

Equine infectious anemia : prevalence in working equids of livestock herds, in Minas Gerais, Brazil

Estimaram-se, no estado de Minas Gerais, a prevalência e a distribuição espacial da anemia infecciosa eqüina (AIE) em propriedades com eqüídeos de serviço. As amostras de sangue, de 6540 eqüídeos de 1940 rebanhos foram coletadas no período de setembro de 2003 a março de 2004, nos 853 municípios do estado. Utilizaram-se dois testes de laboratório em seqüência: ELISA, usando-se antígeno recombinante gp90, e imunodifusão em gel de ágar (IDGA). As prevalências foram de 5,3% [IC=4,3 a 6,3%] para rebanhos e de 3,1% [IC=2,2 a 3,9%] para animais. O estado de Minas Gerais foi considerado área endêmica para AIE. As mais altas prevalências para rebanhos e para animais foram encontradas na região Norte/Noroeste, seguida pela região Vale do Mucuri/Jequitinhonha. ___________________________________________________________________________________________________________ ABSTRACTThe prevalence and spatial distribution of equine infectious anemia (EIA) were estimated in livestock herds where equids were used as draft power and for transportation in the State of Minas Gerais, Brazil. Serum samples were collected from September/2003 to March/2004 in 853 municipalities of the state. The sample comprised 6,540 equids from 1,940 herds. Two laboratorial tests were performed in sequence: ELISA using a recombinant gp90 protein, following by the AGID. The prevalence in the herds was estimated in 5.3% [CI = 4.3 to 6.3%], and 3.1% [CI = 2.2 to 3.9%] of the animals tested were positive. Minas Gerais was considered an endemic region for EIA. The highest prevalence for herds and animals was found in North/Northwest region (strata) followed by Vale do Mucuri/Jequitinhonha region

Magnetocaloric Effect Due To Spin Reorientation In The Crystalline Electrical Field: Theory Applied To Dy Al2

We report a way of obtaining the magnetocaloric effect due to the crystal electrical-field quenching of the total angular momentum in a magnetic system where a strong spin reorientation is present. The theoretical model is applied to Dy Al2 and the results predict a considerable magnetic entropy change by rotating a single crystal in a fixed magnetic field. The obtained temperature and magnetic-field dependencies of the magnetization component along the 111-crystallographic direction are in good agreement with the recently reported experimental data. © 2007 The American Physical Society.7518Pecharsky, V.K., Gschneidner Jr., K.A., (1997) Phys. Rev. Lett., 78, p. 4494. , PRLTAO 0031-9007 10.1103/PhysRevLett.78.4494Choe, W., Pecharsky, V.K., Pecharsky, A.O., Gschneidner Jr., K.A., Young Jr., V.G., Miller, G.J., (2000) Phys. Rev. Lett., 84, p. 4617. , PRLTAO 0031-9007 10.1103/PhysRevLett.84.4617Provenzano, V., Shapiro, A.J., Shull, R.D., (2004) Nature (London), 429, p. 853. , NATUAS 0028-0836 10.1038/nature02657Tegus, O., Brück, E., Buschow, K.H.J., De Boer, F.R., (2002) Nature (London), 415, p. 150. , NATUAS 0028-0836 10.1038/415150AWada, H., Tanabe, Y., (2001) Appl. Phys. Lett., 79, p. 3302. , APPLAB 0003-6951 10.1063/1.1419048Wada, H., Morikawa, T., Taniguchi, K., Shibata, T., Yamada, Y., Akishige, Y., (2003) Physica B, 328, p. 114. , PHYBE3 0921-4526 10.1016/S0921-4526(02)01822-7Hu, F., Shen, B., Sun, J., Cheng, Z., Rao, G., Zhang, X., (2001) Appl. Phys. Lett., 78, p. 3675. , APPLAB 0003-6951 10.1063/1.1375836Fujita, A., Fujieda, S., Hasegawa, Y., Fukamichi, K., (2003) Phys. Rev. B, 67, p. 104416. , PRBMDO 0163-1829 10.1103/PhysRevB.67.104416Von Ranke, P.J., De Oliveira, N.A., Gama, S., (2004) J. Magn. Magn. Mater., 277, p. 78. , JMMMDC 0304-8853 10.1016/j.jmmm.2003.10.013Von Ranke, P.J., De Campos, N.A., Caron, L., Coelho, A.A., Gama, S., De Oliveira, N.A., (2004) Phys. Rev. B, 70, p. 094410. , PRBMDO 0163-1829 10.1103/PhysRevB.70.094410Von Ranke, P.J., De Oliveira, N.A., Gama, S., (2004) Phys. Lett. a, 320, p. 302. , PYLAAG 0375-9601 10.1016/j.physleta.2003.10.067Gama, S., Coelho, A.A., De Campos, A., Carvalho, A.M., Gandra, F.C.G., Von Ranke, P.J., De Oliveira, N.A., (2004) Phys. Rev. Lett., 93, p. 237202. , PRLTAO 0031-9007 10.1103/PhysRevLett.93.237202Von Ranke, P.J., De Oliveira, N.A., Mello, C., Carvalho, A.M., Gama, S., (2005) Phys. Rev. B, 71, p. 054410. , PRBMDO 0163-1829 10.1103/PhysRevB.71.054410Von Ranke, P.J., Gama, S., Coelho, A.A., De Campos, A., Carvalho, A.M., Gandra, F.C.G., De Oliveira, N.A., (2006) Phys. Rev. B, 73, p. 014415. , PRBMDO 0163-1829 10.1103/PhysRevB.73.014415Von Ranke, P.J., Pecharsky, V.K., Gschneidner, K.A., Korte, B.J., (1998) Phys. Rev. B, 58, p. 14436. , PRBMDO 0163-1829 10.1103/PhysRevB.58.14436Von Ranke, P.J., Mota, M.A., Grangeia, D.F., Carvalho, A.M., Gandra, F.C.G., Coelho, A.A., Caldas, A., Gama, S., (2004) Phys. Rev. B, 70, p. 134428. , PRBMDO 0163-1829 10.1103/PhysRevB.70.134428Lima, A.L., Oliveira, I.S., Gomes, A.M., Von Ranke, P.J., (2002) Phys. Rev. B, 65, p. 172411. , PRBMDO 0163-1829 10.1103/PhysRevB.65.172411Von Ranke, P.J., Lima, A.L., Nobrega, E.P., Da Silva, X.A., Guimarães, A.P., Oliveira, I.S., (2000) Phys. Rev. B, 63, p. 024422. , PRBMDO 0163-1829 10.1103/PhysRevB.63.024422Lima, A.L., Tsokol, A.O., Gschneidner Jr., K.A., Pecharky, V.K., Lograsso, T.A., Schlagel, D.L., (2005) Phys. Rev. B, 72, p. 024403. , PRBMDO 0163-1829 10.1103/PhysRevB.72.024403Von Ranke, P.J., De Oliveira, I.G., Guimarães, A.P., Da Silva, X.A., (2000) Phys. Rev. B, 61, p. 447. , PRBMDO 0163-1829 10.1103/PhysRevB.61.447Bak, P., (1974) J. Phys. C, 7, p. 4097. , JPSOAW 0022-3719 10.1088/0022-3719/7/22/014Hutchings., M.T., (1964) Solid State Phys., 16, p. 227. , SSPHAE 0081-1947Lea, K.R., Leask, M.J.M., Wolf, W.P., (1962) J. Phys. Chem. Solids, 33, p. 1381. , JPCSAW 0022-3697Stevens, K.W.H., (1952) Proc. Phys. Soc., London, Sect. a, 65, p. 209. , PPSAAM 0370-1298 10.1088/0370-1298/65/3/308Purwins, H.G., Leson, A., (1990) Adv. Phys., 39, p. 309. , ADPHAH 0001-8732 10.1080/00018739000101511Kuz'Min, M.D., Tishin, A.M., (1991) J. Phys. D, 24, p. 2039. , JPAPBE 0022-3727 10.1088/0022-3727/24/11/02

Faktor Resiko Terjadinya Perdarahan Post Partum : Studi Literatur

Maternal mortality rate in Indonesia is relatively high. The most common cause of maternal death is bleeding. Post partum haemorrhage (PPH) is an unexpected cause and the fastest cause of maternal death worldwide. PPH is blood loss of 500 cc or more that occurs after the baby is born. Risk factors/predisposition for postpartum hemorrhage include: anemia, parity, gestational age, delivery distance, excessive uterine stretching (macrosomia, gemely, and polyhidramnions), precipitate parturition, oxytocin induction, history of cesarean section, ante partum bleeding, first stage of labor and the elongated II, and so on. This literature review aims to determine the risk factors/trigger factors of postpartum hemorrhage. Using literature study according to the topic. Literature studies were obtained from various sources, including from journals ranging from 2015-2020. Source articles from goggle scholars and Goggle Scholars. From several journals that have been reviewed, postpartum hemorrhage is one of the complications that has a high incidence. And there is a relationship between predisposing factors and the incidence of postpartum hemorrhageAbstrakAngka kematian ibu melahirkan di Indonesia relatif tinggi. Adapun penyebab terbanyak yang menyebabkan kematian ibu adalah perdarahan. Perdarahan post partum adalah penyebab tak terduga dan penyebab tercepat kematian ibu diseluruh dunia. Perdarahan post partum adalah hilangnya darah 500 cc atau lebih yang terjadi setelah bayi lahir. Faktor resiko/predisposisi terjadinya perdarahan post partum antara lain : anemia, paritas, umur kehamilan, jarak persalinan, peregangan uterus yang berlebihan (makrosomia, gemeli dan polihidramnion), partus presipitatus, induksi oksitosin, riwayat seksio secaria, perdarahan ante partum, persalinan kalan I dan II yang memanjang, dan lain-lain. literatur review ini bertujuan untuk mengetahui faktor resiko/faktor pencetus dari perdarahan post partum. menggunakan studi literatur sesuai dengan topik. Studi literatur didapat dari berbagai sumber, diantaranya dari jurnal berkisar tahun 2014-2018. Sumber artikel dari Pubmed, Portal Garuda dan goggle Scholar. dari beberapa jurnal yang telah ditelaah, perdarahan post partum merupakan salah satu komplikasi yang angka kejadiannya masih tinggi. Dan ada hubungan antara faktor predisposisi dengan kejadian perdarahan post partu

Faktor Resiko Terjadinya Perdarahan Post Partum : Studi Literatur

Maternal mortality rate in Indonesia is relatively high. The most common cause of maternal death is bleeding. Post partum haemorrhage (PPH) is an unexpected cause and the fastest cause of maternal death worldwide. PPH is blood loss of 500 cc or more that occurs after the baby is born. Risk factors/predisposition for postpartum hemorrhage include: anemia, parity, gestational age, delivery distance, excessive uterine stretching (macrosomia, gemely, and polyhidramnions), precipitate parturition, oxytocin induction, history of cesarean section, ante partum bleeding, first stage of labor and the elongated II, and so on. This literature review aims to determine the risk factors/trigger factors of postpartum hemorrhage. Using literature study according to the topic. Literature studies were obtained from various sources, including from journals ranging from 2015-2020. Source articles from goggle scholars and Goggle Scholars. From several journals that have been reviewed, postpartum hemorrhage is one of the complications that has a high incidence. And there is a relationship between predisposing factors and the incidence of postpartum hemorrhageAbstrakAngka kematian ibu melahirkan di Indonesia relatif tinggi. Adapun penyebab terbanyak yang menyebabkan kematian ibu adalah perdarahan. Perdarahan post partum adalah penyebab tak terduga dan penyebab tercepat kematian ibu diseluruh dunia. Perdarahan post partum adalah hilangnya darah 500 cc atau lebih yang terjadi setelah bayi lahir. Faktor resiko/predisposisi terjadinya perdarahan post partum antara lain : anemia, paritas, umur kehamilan, jarak persalinan, peregangan uterus yang berlebihan (makrosomia, gemeli dan polihidramnion), partus presipitatus, induksi oksitosin, riwayat seksio secaria, perdarahan ante partum, persalinan kalan I dan II yang memanjang, dan lain-lain. literatur review ini bertujuan untuk mengetahui faktor resiko/faktor pencetus dari perdarahan post partum. menggunakan studi literatur sesuai dengan topik. Studi literatur didapat dari berbagai sumber, diantaranya dari jurnal berkisar tahun 2014-2018. Sumber artikel dari Pubmed, Portal Garuda dan goggle Scholar. dari beberapa jurnal yang telah ditelaah, perdarahan post partum merupakan salah satu komplikasi yang angka kejadiannya masih tinggi. Dan ada hubungan antara faktor predisposisi dengan kejadian perdarahan post partu

Branching Fractions for D0 -> K+K- and D0 -> pi+pi-, and a Search for CP Violation in D0 Decays

Using the large hadroproduced charm sample collected in experiment E791 at Fermilab, we have measured ratios of branching fractions for the two-body singly-Cabibbo-suppressed charged decays of the D0: (D0 -> KK)/(D0 -> Kpi) = 0.109 +- 0.003 +- 0.003, (D0 -> pipi)/(D0 -> Kpi) = 0.040 +- 0.002 +- 0.003, and (D0 -> KK)/(D0 -> pipi) = 2.75 +- 0.15 +- 0.16. We have looked for differences in the decay rates of D0 and D0bar to the CP eigenstates K+K- and pi+pi-, and have measured the CP asymmetry parameters A_CP(K+K-) = -0.010 +- 0.049 +- 0.012 and A_CP(pi+pi-) = -0.049 +- 0.078 +- 0.030, both consistent with zero.Comment: 10 Postscript pages, including 2 figures. Submitted to Phys. Lett.

Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis

PI3K activation plays a central role in the development of pulmonary inflammation and tissue remodeling. PI3K inhibitors may thus offer an improved therapeutic opportunity to treat non-resolving lung inflammation but their action is limited by unwanted on-target systemic toxicity. Here we present CL27c, a prodrug pan-PI3K inhibitor designed for local therapy, and investigate whether inhaled CL27c is effective in asthma and pulmonary fibrosis. Mice inhaling CL27c show reduced insulin-evoked Akt phosphorylation in lungs, but no change in other tissues and no increase in blood glycaemia, in line with a local action. In murine models of acute or glucocorticoid-resistant neutrophilic asthma, inhaled CL27c reduces inflammation and improves lung function. Finally, inhaled CL27c administered in a therapeutic setting protects from bleomycin-induced lung fibrosis, ultimately leading to significantly improved survival. Therefore, local delivery of a pan-PI3K inhibitor prodrug reduces systemic on-target side effects but effectively treats asthma and irreversible pulmonary fibrosis

Search for CP Violation in Charged D Meson Decays

We report results of a search for CP violation in the singly Cabibbo-suppressed decays D+ -> K- K+ pi+, phi pi+, K*(892)0 K+, and pi- pi+ pi+ based on data from the charm hadroproduction experiment E791 at Fermilab. We search for a difference in the D+ and D- decay rates for each of the final states. No evidence for a difference is seen. The decay rate asymmetry parameters A(CP), defined as the difference in the D+ and D- decay rates divided by the sum of the decay rates, are measured to be: A(CP)(K K pi) = -0.014 +/- 0.029, A(CP)(phi pi) = -0.028 +/- 0.036, A(CP)(K*(892) K) = -0.010 +/- 0.050, and A(CP)(pi pi pi) = -0.017 +/- 0.042.Comment: 13 pages, 5 figures, 1 table; Elsevier LaTe

Asymmetries between the production of D+ and D- mesons from 500 GeV/c pi- nucleon interactions as a function of xF and pt**2

We present asymmetries between the production of D+ and D- mesons in Fermilab experiment E791 as a function of xF and pt**2. The data used here consist of 74,000 fully-reconstructed charmed mesons produced by a 500 GeV/c pi- beam on C and Pt foils. The measurements are compared to results of models which predict differences between the production of heavy-quark mesons that have a light quark in common with the beam (leading particles) and those that do not (non-leading particles). While the default models do not agree with our data, we can reach agreement with one of them, PYTHIA, by making a limited number of changes to parameters used